SCHEMBL23965681

SCHEMBL23965681

COC(=O)C(=N)c1cccc(C)c1CO/N=C(\C)c1ccccc1C(C)C

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 2/20 0.34
KCNK9 Q9NPC2 2/20 0.34
MAPK1 P28482 1/20 0.34
GLS O94925 1/20 0.33
HIF1A Q16665 2/20 0.33
NLRP3 Q96P20 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
LPAR1 Q92633 1/20 0.31
POLB P06746 1/20 0.31
HPGD P15428 1/20 0.31
SLC22A12 Q96S37 1/20 0.31
CTSA P10619 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23972107 0.86 HIF1A (0.45) KCNK3KCNK9MAPK1HIF1ANLRP3
SCHEMBL23965638 0.85 HIF1A (0.39) HIF1ALMNAPOLBHPGD
SCHEMBL23969505 0.83 TSHR (0.35) KCNK3KCNK9HIF1AMEN1KMT2A
SCHEMBL23977993 0.81 HIF1A (0.41) KCNK3KCNK9HIF1ALMNAGAA
SCHEMBL23972130 0.81 HIF1A (0.35) KCNK3KCNK9MAPK1HIF1ANLRP3
SCHEMBL25721762 0.79 MAPK1 (0.35) KCNK3KCNK9MAPK1NLRP3MEN1
SCHEMBL23965627 0.78 HIF1A (0.34) KCNK3KCNK9HIF1AMEN1KMT2A
SCHEMBL23971728 0.76 HIF1A (0.51) HIF1AGAA
SCHEMBL23972055 0.76 HIF1A (0.48) KCNK3KCNK9HIF1AMEN1KMT2A
SCHEMBL25601878 0.74 HIF1A (0.41) HIF1ALMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3903583-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS III BASF SE (DE) 2021-11-03 EP disclosed