Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969505 | 0.87 | TSHR (0.35) | HIF1ARAB9ANPC1KCNK3KCNK9 | |
| SCHEMBL23971878 | 0.86 | HIF1A (0.54) | HIF1ARAB9ANPC1KCNK3KCNK9 | |
| SCHEMBL25552201 | 0.85 | HIF1A (0.39) | HIF1ARAB9ANPC1KCNK3KCNK9 | |
| SCHEMBL23965638 | 0.81 | HIF1A (0.39) | HIF1ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL23965681 | 0.81 | KCNK3 (0.34) | HIF1AKCNK3KCNK9LMNAGAA | |
| SCHEMBL23971871 | 0.81 | HIF1A (0.43) | HIF1ARAB9ANPC1KCNK3KCNK9 | |
| SCHEMBL23971575 | 0.80 | HIF1A (0.59) | HIF1ARAB9ANPC1PPARGPPARA | |
| SCHEMBL23971626 | 0.79 | HIF1A (0.50) | HIF1ARAB9ANPC1PPARGPPARA | |
| SCHEMBL25667318 | 0.78 | PPARG (0.42) | RAB9ANPC1SMN1; SMN2PPARGPPARA | |
| SCHEMBL23979194 | 0.78 | HIF1A (0.54) | HIF1ARAB9ANPC1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903581-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS I | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |