Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23972106 | 0.86 | HIF1A (0.52) | HIF1AHPGDSMN1; SMN2PRMT5LMNA | |
| SCHEMBL23965681 | 0.85 | KCNK3 (0.34) | HIF1AHPGDLMNAPOLB | |
| SCHEMBL23965634 | 0.84 | P2RX7 (0.35) | HIF1APRMT5HDAC3HDAC1 | |
| SCHEMBL23969505 | 0.83 | TSHR (0.35) | HIF1AHPGDSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23977993 | 0.81 | HIF1A (0.41) | HIF1ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23971864 | 0.81 | HIF1A (0.41) | HIF1AHPGDSMN1; SMN2PRMT5LMNA | |
| SCHEMBL23972077 | 0.79 | HIF1A (0.50) | HIF1AHPGDSMN1; SMN2LMNAHTT | |
| SCHEMBL23972055 | 0.76 | HIF1A (0.48) | HIF1APOLB | |
| SCHEMBL23971728 | 0.76 | HIF1A (0.51) | HIF1AALDH1A1 | |
| SCHEMBL26497148 | 0.73 | HIF1A (0.47) | HIF1AHPGDLMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903582-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS II | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |
| EP-3903583-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS III | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |