Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23977993 | 0.87 | HIF1A (0.41) | SMN1; SMN2ALDH1A1MAPTGAAHIF1A | |
| SCHEMBL23971676 | 0.86 | HIF1A (0.45) | SMN1; SMN2HPGDALDH1A1MAPTGAA | |
| SCHEMBL23965681 | 0.83 | KCNK3 (0.34) | HPGDGAAHIF1AKMT2AMEN1 | |
| SCHEMBL23965638 | 0.83 | HIF1A (0.39) | SMN1; SMN2HPGDALDH1A1HIF1APOLB | |
| SCHEMBL23971865 | 0.81 | HIF1A (0.35) | TSHRCYP3A4CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL23972055 | 0.78 | HIF1A (0.48) | HIF1AKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL25600861 | 0.78 | HIF1A (0.43) | SMN1; SMN2HPGDALDH1A1MAPTHIF1A | |
| SCHEMBL25598281 | 0.76 | HIF1A (0.46) | CYP2D6CYP2C19SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL25599202 | 0.76 | HIF1A (0.43) | SMN1; SMN2MAPTHIF1ARAB9ANPC1 | |
| SCHEMBL25601892 | 0.76 | HIF1A (0.45) | SMN1; SMN2HPGDALDH1A1MAPTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903582-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS II | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |