Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 3/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718523 | 0.87 | MAPT (0.56) | CALM1LMNASMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL9081470 | 0.87 | LMNA (0.61) | LMNASMN1; SMN2MAPTCYP3A4KDM4E | |
| SCHEMBL10183475 | 0.85 | CYP3A4 (0.60) | CALM1LMNASMN1; SMN2CYP3A4NPC1 | |
| SCHEMBL717746 | 0.83 | GABRA1 (0.54) | CALM1SMN1; SMN2MAPTCYP3A4KDM4E | |
| SCHEMBL10183554 | 0.83 | LMNA (0.58) | LMNASMN1; SMN2MAPTCYP3A4KDM4E | |
| SCHEMBL13252213 | 0.81 | LMNA (0.56) | CALM1LMNASMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL717987 | 0.80 | NPC1 (0.65) | LMNASMN1; SMN2MAPTKMT2ANPC1 | |
| SCHEMBL10182922 | 0.80 | PTGS2 (0.49) | LMNASMN1; SMN2MAPTCYP3A4KDM4E | |
| SCHEMBL23894744 | 0.80 | LMNA (0.57) | CALM1LMNASMN1; SMN2MAPTNPC1 | |
| SCHEMBL320560 | 0.79 | CYP3A4 (0.63) | LMNASMN1; SMN2MAPTCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11160766-B2 | Peritoneal therapeutic fluid | OPTERION HEALTH AG (CH) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11160766-B2 | Peritoneal therapeutic fluid | FABP6, ALB, FABP2 | CALM1 2133/4885LTA4H 3174/4885LMNA 4496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.