Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 5/20 | 0.50 |
| ▸ | CTSS | P25774 | 4/20 | 0.50 |
| ▸ | CTSK | P43235 | 4/20 | 0.50 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
| ▸ | ECE1 | P42892 | 2/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15601856 | 0.86 | POLB (0.55) | POLBCTSLCTSSCTSKCTSB | |
| SCHEMBL8671882 | 0.86 | CTSL (0.63) | CTSLCTSSCTSKCTSBECE1 | |
| SCHEMBL2978398 | 0.86 | CTSL (0.63) | CTSLCTSSCTSKCTSBECE1 | |
| SCHEMBL1287168 | 0.86 | CTSL (0.63) | CTSLCTSSCTSKCTSBECE1 | |
| SCHEMBL220569 | 0.86 | CTSL (0.63) | CTSLCTSSCTSKCTSBECE1 | |
| SCHEMBL6150431 | 0.86 | ADAMTS4 (0.53) | CTSLCTSSCTSKCTSBECE1 | |
| SCHEMBL6148841 | 0.86 | ADAMTS4 (0.53) | CTSLCTSSCTSKCTSBECE1 | |
| SCHEMBL8604954 | 0.83 | CTSL (0.51) | CTSLCTSSCTSKCTSBECE1 | |
| SCHEMBL19607509 | 0.83 | CTSL (0.55) | CTSLCTSSCTSKCTSBECE1 | |
| Isopropylamine SCHEMBL10558459 | 0.82 | CTSL (0.59) | CTSLCTSSCTSKCTSBECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083619-B1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | ASANA BIOSCIENCES LLC (US) | 2021-11-03 | — | — | EP | disclosed |