Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LATS1 | O95835 | 2/20 | 0.40 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16828900 | 0.82 | RAB9A (0.43) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL21579239 | 0.81 | RAB9A (0.47) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL14099640 | 0.75 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDHSD17B10LATS1 | |
| SCHEMBL3825817 | 0.74 | GRM5 (0.43) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL11578570 | 0.74 | GRM5 (0.43) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL27354404 | 0.74 | CA12 (0.42) | KDM4EALDH1A1HPGDCA12CA1 | |
| SCHEMBL11263883 | 0.74 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| Hydrochloric Acid SCHEMBL10559703 | 0.73 | GRM5 (0.42) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL29745125 | 0.71 | — | — | |
| SCHEMBL2947216 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083619-B1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | ASANA BIOSCIENCES LLC (US) | 2021-11-03 | — | — | EP | disclosed |