Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | RHEB | Q15382 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23909001 | 0.87 | XDH (0.38) | — | |
| SCHEMBL23914589 | 0.87 | SCN9A (0.33) | LMNAMAPK1CNR2RHEBMEN1 | |
| SCHEMBL23966549 | 0.87 | DGAT1 (0.34) | DGAT1CNR2 | |
| SCHEMBL23909013 | 0.85 | XDH (0.38) | — | |
| SCHEMBL23966548 | 0.83 | DGAT1 (0.34) | DGAT1CNR2 | |
| SCHEMBL23915306 | 0.79 | XDH (0.36) | — | |
| SCHEMBL23914757 | 0.78 | XDH (0.36) | DGAT1 | |
| SCHEMBL23914673 | 0.77 | SCN9A (0.33) | SCN9A | |
| SCHEMBL23914756 | 0.77 | CNR2 (0.32) | DGAT1CNR2 | |
| SCHEMBL23909131 | 0.76 | XDH (0.36) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |