Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23966548 | 0.96 | DGAT1 (0.34) | DGAT1CNR2PDE4BNPC1CNR1 | |
| SCHEMBL23908843 | 0.89 | XDH (0.39) | DGAT1 | |
| SCHEMBL23966541 | 0.87 | DGAT1 (0.32) | DGAT1CNR2 | |
| SCHEMBL23915573 | 0.85 | SCN9A (0.33) | CNR2PDE4B | |
| SCHEMBL23966550 | 0.85 | CNR2 (0.32) | CNR2PDE4B | |
| SCHEMBL23914609 | 0.78 | XDH (0.38) | — | |
| SCHEMBL23966834 | 0.76 | XDH (0.38) | CNR2 | |
| SCHEMBL23914853 | 0.76 | XDH (0.38) | — | |
| SCHEMBL23909001 | 0.75 | XDH (0.38) | — | |
| SCHEMBL23914589 | 0.75 | SCN9A (0.33) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |