Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15371814 | 0.83 | RECQL (0.44) | RECQLTDP1ADRB2ADRB1ADRB3 | |
| SCHEMBL19825352 | 0.83 | RECQL (0.44) | RECQLTDP1ADRB2ADRB1ADRB3 | |
| SCHEMBL19825375 | 0.79 | RECQL (0.43) | RECQLTDP1ADRB2ADRB1ADRB3 | |
| SCHEMBL17023988 | 0.73 | CYP3A4 (0.42) | RECQLTDP1KMT2ALMNACYP1A2 | |
| SCHEMBL21769359 | 0.72 | RECQL (0.43) | RECQLTDP1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL7172501 | 0.70 | RECQL (0.44) | RECQLTDP1ADRB2ADRB1ADRB3 | |
| SCHEMBL5215244 | 0.70 | APP (0.49) | TDP1XBP1ADRB2ADRB1ADRB3 | |
| SCHEMBL7366077 | 0.70 | KMT2A (0.41) | TDP1XBP1KMT2ALMNACYP2C19 | |
| SCHEMBL7412821 | 0.70 | KMT2A (0.41) | TDP1XBP1KMT2ALMNACYP2C19 | |
| SCHEMBL3152114 | 0.70 | ALDH1A1 (0.39) | RECQLTDP1CYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |