Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23616359 | 0.78 | NFKB1 (0.40) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL12067919 | 0.75 | TDP1 (0.52) | TDP1MAPTPPARGPPARACA12 | |
| SCHEMBL21161629 | 0.73 | CA12 (0.49) | RECQLTDP1MAPTCA12CA1 | |
| SCHEMBL21161191 | 0.73 | CA12 (0.49) | RECQLTDP1MAPTCA12CA1 | |
| SCHEMBL21161661 | 0.73 | CA12 (0.49) | RECQLTDP1MAPTCA12CA1 | |
| SCHEMBL23966869 | 0.72 | RECQL (0.38) | RECQLTDP1PPARGPPARACYP1A2 | |
| SCHEMBL19675061 | 0.71 | ALDH1A1 (0.42) | RECQLTDP1MAPTRAB9ACYP1A2 | |
| SCHEMBL29167216 | 0.71 | ALDH1A1 (0.42) | RECQLTDP1MAPTRAB9ACYP1A2 | |
| SCHEMBL17147606 | 0.71 | PPARG (0.39) | TDP1MAPTPPARGPPARACA12 | |
| SCHEMBL178373 | 0.70 | CYP17A1 (0.54) | TDP1MAPTCA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197276-B1 | HERBICIDAL PYRIDINO-/PYRIMIDINO-THIAZOLES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| EP-3772516-B1 | TROPOMYOSIN RECEPTOR KINASE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | JIANGSU VCARE PHARMATECH CO LTD (CN) | 2022-12-14 | — | — | EP | disclosed |
| EP-3842425-A1 | NOVEL QUINOLINE DERIVATIVE INHIBITOR | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-06-30 | — | — | EP | disclosed |
| EP-3772516-A1 | TROPOMYOSIN RECEPTOR KINASE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Vcare Pharmatech Co., Ltd (CN) | 2021-02-10 | — | — | EP | disclosed |
| WO-2020038460-A1 | NOVEL QUINOLINE DERIVATIVE INHIBITOR | 南京药捷安康生物科技有限公司 | 2020-02-27 | — | — | WO | disclosed |