SCHEMBL23966870

SCHEMBL23966870

Cc1ccc(SOC(C)C)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
MAPT P10636 3/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HKDC1 Q2TB90 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
DNMT1 P26358 1/20 0.34
HPGD P15428 7/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.31
BCL2 P10415 1/20 0.31
MCL1 Q07820 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
DDB1 Q16531 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22341499 0.79 MAOA (0.44) ALDH1A1LMNABCL2MCL1
SCHEMBL21035917 0.78 MAOA (0.40) TDP1MAPTL3MBTL1HPGDALDH1A1
SCHEMBL9544764 0.77 CA1 (0.48) ACHETDP1MAPTNPSR1L3MBTL1
SCHEMBL9544755 0.76
SCHEMBL19404158 0.76 ALDH1A1 (0.38) ACHEMAPTMEN1KMT2AHPGD
SCHEMBL6677383 0.74 MAPT (0.33) TDP1MAPTMEN1KMT2AHKDC1
SCHEMBL14685179 0.74 ACHE (0.47) ACHETDP1MAPTMEN1KMT2A
SCHEMBL15349493 0.73 HPGD (0.35) HPGDUSP2
SCHEMBL8265860 0.72 ACHE (0.44) ACHETDP1MAPTMEN1KMT2A
SCHEMBL24103381 0.72 HPGD (0.33) ACHEMAPTMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4010352-B1 A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES GYROS PROTEIN TECH AB (SE) 2023-10-18 EP disclosed
EP-4206175-A1 PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND Hua Medicine (Shanghai) Ltd. (CN) 2023-07-05 EP disclosed
EP-3649119-B1 NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS GALAPAGOS NV (BE) 2021-11-03 EP disclosed