SCHEMBL23967897

SCHEMBL23967897

Fc1cccc2c1oc1c(I)cccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.33
RAB9A P51151 4/20 0.33
GPR84 Q9NQS5 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
AHR P35869 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
PARP1 P09874 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2937953 0.87 AHR (0.38) NPC1RAB9AGPR84HPGDSMN1; SMN2
SCHEMBL1539087 0.87 AHR (0.38) AHR
SCHEMBL19452850 0.82 CYP1A1 (0.32) NPC1RAB9A
SCHEMBL18820546 0.75 LOXL2 (0.40) AHRPARP1
SCHEMBL29709172 0.75 LOXL2 (0.40) AHRPARP1
SCHEMBL24627319 0.75 AHR (0.56) HPGDSMN1; SMN2AHR
SCHEMBL18818726 0.75 MCL1 (0.44) SMN1; SMN2AHRCA1CA2CA9
SCHEMBL23280737 0.75 ALDH1A1 (0.42) NPC1RAB9AHPGDSMN1; SMN2AHR
SCHEMBL16261667 0.75 ACHE (0.44) NPC1RAB9A
SCHEMBL19452856 0.75 ESR1 (0.33) NPC1RAB9AHPGDSMN1; SMN2AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed