Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23965666 | 0.86 | HPGD (0.38) | GABRA1GABRG2GABRB3CYP3A4CYP2C19 | |
| SCHEMBL23965600 | 0.78 | HPGD (0.38) | CYP3A4ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL23965622 | 0.78 | HPGD (0.36) | CYP3A4CYP2C19ALDH1A1HPGDKDM4E | |
| SCHEMBL23965678 | 0.75 | — | — | |
| SCHEMBL357603 | 0.75 | GABRA1 (0.48) | GABRA1GABRG2GABRB3ALDH1A1HPGD | |
| SCHEMBL5963706 | 0.73 | ALDH1A1 (0.57) | CYP3A4ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL27409195 | 0.72 | ALDH1A1 (0.55) | CYP3A4ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL30585075 | 0.72 | CD38 (0.46) | CYP3A4ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL23965589 | 0.71 | HPGD (0.38) | CYP3A4ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL28349153 | 0.68 | ALDH1A1 (0.37) | CYP3A4CYP2C19ALDH1A1KDM4EPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903584-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS IV | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |