SCHEMBL28349153

SCHEMBL28349153

CC(=N)C(=N)Cc1c(C)cccc1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
TRPA1 O75762 2/20 0.33
CYP2A6 P11509 2/20 0.33
HTR1D P28221 2/20 0.33
CYP1A2 P05177 1/20 0.33
HTR1B P28222 1/20 0.33
ATM Q13315 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
TSHR P16473 1/20 0.32
ACHE P22303 1/20 0.32
SLC22A12 Q96S37 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
TAAR1 Q96RJ0 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2725995 0.77 ALDH1A1 (0.43) ALDH1A1TRPA1CYP2A6HTR1DCYP1A2
SCHEMBL28352767 0.74 GABRA1 (0.53) CYP1A2CA1CA2TSHRKMT2A
SCHEMBL1258876 0.73 KDM4E (0.41) ALDH1A1TRPA1CYP2A6CYP1A2ATM
SCHEMBL15304521 0.73 KDM4E (0.41) ALDH1A1CYP2A6CYP1A2TSHRSLC22A12
SCHEMBL16223491 0.72 ALDH1A1 (0.36) ALDH1A1TRPA1CYP2A6HTR1DCYP1A2
SCHEMBL9267218 0.71 KDM4E (0.40) ALDH1A1TRPA1CYP2A6CYP1A2SLC22A12
SCHEMBL4686503 0.71 PSMB5 (0.40) ALDH1A1TRPA1CYP2A6CYP1A2SLC22A12
SCHEMBL12214127 0.70 KDM4E (0.42) ALDH1A1TRPA1CYP2A6CYP1A2ATM
SCHEMBL28443970 0.69 MAPT (0.36) ALDH1A1TRPA1HTR1DCYP1A2HTR1B
SCHEMBL1004574 0.68 KDM4E (0.58) ALDH1A1CYP1A2SLC22A12KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117693496-A Oligomerization process in a reactor having a variable diameter zone comprising a step of recycling pre-cooled solvent IFP 新能源公司 2024-03-12 CN disclosed
CN-112533889-B Process for oligomerization in cascade with stirred gas-liquid reactor staged injection of ethylene IFP 新能源公司 2024-03-05 CN disclosed
CN-117120401-A Oligomerization process comprising a step of recycling pre-cooled solvent IFP 新能源公司 2023-11-24 CN disclosed
CN-114761118-B Gas/liquid oligomerization reactor having continuous zones of varying diameter IFP 新能源公司 2023-11-07 CN disclosed
CN-116997410-A Method for oligomerization in a reactor comprising a gas/liquid double distributor IFP 新能源公司 2023-11-03 CN disclosed
CN-116685395-A Gas/liquid oligomerization reactor comprising a central tube IFP 新能源公司 2023-09-01 CN disclosed
CN-110891926-B Oligomerization process using vortexes IFP 新能源公司 2023-08-04 CN disclosed
CN-116390807-A Oligomerization process using gaseous headspace recycle IFP 新能源公司 2023-07-04 CN disclosed
CN-114761114-A Gas/liquid oligomerization reactor comprising transverse internals IFP 新能源公司 2022-07-15 CN disclosed
CN-114761118-A Gas/liquid oligomerization reactor with continuous zones of varying diameter IFP 新能源公司 2022-07-15 CN disclosed
CN-110913982-B Oligomerization process using a reaction apparatus comprising a dispersion member IFP 新能源公司 2022-05-24 CN disclosed
CN-114174246-A Oligomerization process with gaseous headspace recycle IFP 新能源公司 2022-03-11 CN disclosed
CN-112533889-A Method for oligomerisation in cascade of stirred gas-liquid reactors with staged ethylene injection IFP 新能源公司 2021-03-19 CN disclosed
CN-110913982-A Oligomerization process using a reaction apparatus comprising a dispersion member IFP 新能源公司 2020-03-24 CN disclosed
CN-110891926-A Oligomerization process using vortexes IFP 新能源公司 2020-03-17 CN disclosed
CN-110652940-A Ethylene oligomerization process employing stirred gas/liquid reactor and plug flow reactor sequences IFP 新能源公司 2020-01-07 CN disclosed