Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23965654 | 0.79 | GAA (0.40) | HPGDLMNAL3MBTL1GAANPC1 | |
| SCHEMBL3135001 | 0.75 | LMNA (0.52) | HPGDLMNAL3MBTL1GAANPC1 | |
| SCHEMBL23965683 | 0.73 | LMNA (0.46) | HPGDLMNAL3MBTL1GAANPC1 | |
| SCHEMBL19969993 | 0.72 | CNR1 (0.41) | BAZ2BPARP1 | |
| SCHEMBL619877 | 0.71 | ALDH1A1 (0.52) | HPGDLMNAL3MBTL1GAANPC1 | |
| SCHEMBL8179369 | 0.71 | HPGD (0.49) | HPGDLMNAL3MBTL1GAANPC1 | |
| SCHEMBL9668760 | 0.71 | GAA (0.55) | HPGDLMNAL3MBTL1GAANPC1 | |
| Acetic Acid SCHEMBL27805111 | 0.70 | LMNA (0.47) | HPGDLMNAL3MBTL1GAANPC1 | |
| SCHEMBL22114026 | 0.70 | CTSD (0.39) | HPGDLMNAGAAALDH1A1KDM4E | |
| SCHEMBL7658118 | 0.70 | HPGD (0.44) | HPGDLMNAL3MBTL1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903584-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS IV | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |