Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18606778 | 1.00 | TSHR (0.41) | TSHRALDH1A1HPGDERCC5FEN1 | |
| SCHEMBL14386189 | 0.84 | ALDH1A1 (0.37) | TSHRALDH1A1HPGDERCC5FEN1 | |
| SCHEMBL29906516 | 0.84 | ALDH1A1 (0.37) | TSHRALDH1A1HPGDERCC5FEN1 | |
| SCHEMBL23965676 | 0.83 | ESR1 (0.41) | TSHRALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL8365914 | 0.80 | NPC1 (0.38) | TSHRALDH1A1HPGDERCC5FEN1 | |
| SCHEMBL14289796 | 0.80 | ERCC5 (0.40) | TSHRALDH1A1HPGDERCC5FEN1 | |
| SCHEMBL19512893 | 0.78 | HTT (0.39) | TSHRHPGDERCC5FEN1HTT | |
| SCHEMBL29010737 | 0.77 | CES2 (0.50) | TSHRALDH1A1HPGDERCC5FEN1 | |
| SCHEMBL28812225 | 0.77 | CES2 (0.50) | TSHRALDH1A1HPGDERCC5FEN1 | |
| SCHEMBL27966884 | 0.77 | RAB9A (0.39) | ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903584-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS IV | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |