Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 16/20 | 0.35 |
| ▸ | CA2 | P00918 | 16/20 | 0.35 |
| ▸ | CA9 | Q16790 | 15/20 | 0.35 |
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | CA7 | P43166 | 5/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.35 |
| ▸ | CA3 | P07451 | 4/20 | 0.35 |
| ▸ | CA4 | P22748 | 4/20 | 0.35 |
| ▸ | CA6 | P23280 | 4/20 | 0.35 |
| ▸ | CA5A | P35218 | 4/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28098985 | 0.83 | TSHR (0.56) | TSHRALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL28099123 | 0.83 | TSHR (0.56) | TSHRALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL4300371 | 0.78 | TSHR (0.94) | TSHRALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL4954793 | 0.78 | TSHR (0.94) | TSHRALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL1931795 | 0.78 | TSHR (0.94) | TSHRALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL1335477 | 0.78 | TSHR (0.94) | TSHRALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL4952202 | 0.78 | TSHR (0.94) | TSHRALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL4298840 | 0.78 | TSHR (0.94) | TSHRALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL8592211 | 0.78 | TSHR (0.94) | TSHRALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL3248547 | 0.77 | TSHR (0.71) | TSHRALDH1A1KDM4EUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106723-A2 | ANTI-PAF ANTIBODIES | LPATH, INC. (US) | 2011-09-01 | — | — | WO | disclosed |
| US-20110212088-A1 | ANTI-PAF ANTIBODIES | SABBADINI ROGER A | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212088-A1 | ANTI-PAF ANTIBODIES | PAFAH1B2, PAFAH1B3, PLA2G7 | TSHR 3231/4885ALDH1A1 1356/4885KDM4E 4354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.