SCHEMBL23968658

SCHEMBL23968658

N[C@@H](CS)C(=O)NC[C@H]1CC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)NCCCC[C@H](NC(=O)N[C@@H](CCCC(=O)O)C(=O)O)C(=O)O)CC1

nearest known ligand 0.70

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 14/20 0.70
▸ PLG P00747 3/20 0.51
▸ PRSS1 P07477 3/20 0.51
▸ PRSS2 P07478 3/20 0.51
▸ PRSS3 P35030 3/20 0.51
▸ KMT2A Q03164 1/20 0.48
▸ PLAU P00749 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27306091 0.93 FOLH1 (0.74) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL22883225 0.89 FOLH1 (0.82) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL21310479 0.88 FOLH1 (0.80) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL24334720 0.87 FOLH1 (0.78) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL31635857 0.87 FOLH1 (0.82) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL26001462 0.87 FOLH1 (0.78) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL26178698 0.87 FOLH1 (0.78) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL24374933 0.87 FOLH1 (0.81) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL29679267 0.87 FOLH1 (0.79) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL23553003 0.86 FOLH1 (0.76) FOLH1PLGPRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11160886-B2 Method for labeling of sensitive and thermosensitive targeting biomolecules with technetium based compounds BRACCO IMAGING SPA (IT) 2021-11-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11160886-B2 Method for labeling of sensitive and thermosensitive targeting biomolecules with technetium based compounds PNP, TK1, NT5E FOLH1 239/4885PLG 110/4885PRSS1 909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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