SCHEMBL2396877

SCHEMBL2396877

C=C(CC)C(=O)O.C=CC=CC(C=Cc1ccccc1)=CC#N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.37
NPC1 O15118 1/20 0.37
TDP1 Q9NUW8 3/20 0.36
GLA P06280 1/20 0.36
HAO1 Q9UJM8 1/20 0.36
HDAC3 O15379 4/20 0.36
ALDH1A1 P00352 5/20 0.35
LMNA P02545 4/20 0.35
HDAC1 Q13547 3/20 0.35
HDAC2 Q92769 3/20 0.35
MAPT P10636 3/20 0.35
CYP1A2 P05177 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HDAC4 P56524 2/20 0.35
HDAC8 Q9BY41 2/20 0.35
HDAC6 Q9UBN7 2/20 0.35
TNKS O95271 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC10 Q969S8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Itaconate SCHEMBL11506848 0.88 HAO1 (0.39) TDP1GLAHAO1HDAC3ALDH1A1
Methacrylic Acid SCHEMBL1004605 0.88 GLA (0.43) L3MBTL1NPC1TDP1GLAHAO1
Bicarbonate SCHEMBL278424 0.86 MAPT (0.43) L3MBTL1TDP1GLAHAO1HDAC3
SCHEMBL11324439 0.86 NPC1 (0.33) L3MBTL1NPC1TDP1GLAHDAC3
SCHEMBL19309 0.85 LMNA (0.39) L3MBTL1TDP1GLAHAO1HDAC3
Butadiene SCHEMBL8991739 0.84 LMNA (0.38) L3MBTL1TDP1GLAHAO1HDAC3
SCHEMBL5141317 0.83 HDAC3 (0.47) L3MBTL1TDP1GLAHAO1HDAC3
Phosphoric Acid SCHEMBL4366545 0.82 LMNA (0.39) L3MBTL1TDP1GLAHAO1HDAC3
Acrylonitrile SCHEMBL6375424 0.82 KDM4E (0.37) L3MBTL1TDP1GLAHAO1HDAC3
Acrylonitrile SCHEMBL11458975 0.82 KDM4E (0.37) L3MBTL1TDP1GLAHAO1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2148714-B1 COUPLING ARRANGEMENT FOR A TELESCOPIC DEVICE COLOPLAST AS (DK) 2021-03-03 EP disclosed
EP-2370137-B1 COUPLING ARRANGEMENT FOR A TELESCOPIC DEVICE COLOPLAST AS (DK) 2020-03-11 EP disclosed
EP-3238793-B1 SPORTS DEVICE WITH A PRINTABLE, ABRASION-RESISTANT AND TRANSPARENT SURFACE FILM CPS GMBH (DE) 2018-09-12 EP disclosed
EP-3238793-A1 SPORTS DEVICE WITH A PRINTABLE, ABRASION-RESISTANT AND TRANSPARENT SURFACE FILM CPS GmbH (DE) 2017-11-01 EP disclosed
US-9259551-B2 Coupling arrangement for a telescopic device COLOPLAST A/S (DK) 2016-02-16 US disclosed
US-9249512-B2 Process for coating a surface of a substrate made of nonmetallic material with a metal layer PEGASTECH (FR) 2016-02-02 US disclosed
US-20150111050-A1 PROCESS FOR COATING A SURFACE OF A SUBSTRATE MADE OF NONMETALLIC MATERIAL WITH A METAL LAYER ATOTECH USA, LLC 2015-04-23 US disclosed
US-8962086-B2 Process for coating a surface of a substrate made of nonmetallic material with a metal layer PEGASTECH (FR) 2015-02-24 US disclosed
US-20130289537-A1 Coupling arrangement for a telescopic device COLOPLAST A/S (DK) 2013-10-31 US disclosed
US-8491568-B2 Coupling arrangement for a telescopic device COLOPLAST A/S (DK) 2013-07-23 US disclosed
EP-2370137-A1 COUPLING ARRANGEMENT FOR A TELESCOPIC DEVICE Coloplast A/S (DK) 2011-10-05 EP disclosed
US-20110224653-A1 COUPLING ARRANGEMENT FOR A TELESCOPIC DEVICE COLOPLAST A/S (DK) 2011-09-15 US disclosed
US-20100211049-A1 COUPLING ARRANGEMENT FOR A TELESCOPIC DEVICE COLOPLAST A/S (DK) 2010-08-19 US disclosed
WO-2010054659-A1 COUPLING ARRANGEMENT FOR A TELESCOPIC DEVICE COLOPLAST A/S (DK) 2010-05-20 WO disclosed
EP-2148714-A1 COUPLING ARRANGEMENT FOR A TELESCOPIC DEVICE Coloplast A/S (DK) 2010-02-03 EP disclosed
WO-2008138351-A1 COUPLING ARRANGEMENT FOR A TELESCOPIC DEVICE COLOPLAST A/S (DK) 2008-11-20 WO disclosed
WO-2007118848-A2 METHOD FOR PRODUCTION OF A BIOCOMPATIBLE STRUCTURE IN PARTICULAR FOR PRODUCTION OF AN IMPLANT FRIEDRICH-BAUR-GMBH (DE) 2007-10-25 WO disclosed
EP-0654150-A1 A FLEXOGRAPHIC PRINTING ELEMENT HAVING AN IR ABLATABLE LAYER AND PROCESS FOR MAKING A FLEXOGRAPHIC PRINTING PLATE. DU PONT (US) 1995-05-24 EP disclosed
WO-1994003838-A1 A FLEXOGRAPHIC PRINTING ELEMENT HAVING AN IR ABLATABLE LAYER AND PROCESS FOR MAKING A FLEXOGRAPHIC PRINTING PLATE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-02-17 WO disclosed
US-4744936-A Process for embossing thermoplastic material PLASTIC FILM CORPORATION OF AMERICA (US) 1988-05-17 US disclosed