Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1254699 | 0.74 | KDM4E (0.39) | KDM4EMAPK1CASP1CASP7PTGER1 | |
| SCHEMBL21180919 | 0.74 | CA12 (0.36) | KDM4EPTGER1PTGER4PTGER3ALDH1A1 | |
| SCHEMBL17477638 | 0.73 | GPR35 (0.41) | KDM4EMAPK1CASP1CASP7ALDH1A1 | |
| SCHEMBL19696361 | 0.71 | ADORA2A (0.32) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12641730 | 0.71 | ALDH1A1 (0.37) | KDM4EMAPK1PTGER1PTGER4PTGER3 | |
| SCHEMBL8223402 | 0.69 | ALDH1A1 (0.39) | KDM4EMAPK1ALDH1A1RCE1POLB | |
| SCHEMBL22757234 | 0.68 | ALDH1A1 (0.35) | KDM4EPTGER1PTGER4PTGER3ALDH1A1 | |
| SCHEMBL22114596 | 0.66 | PKM (0.35) | KDM4EPTGER1PTGER4PTGER3ALDH1A1 | |
| SCHEMBL15468971 | 0.66 | POLB (0.36) | KDM4EPTGER1PTGER4PTGER3ALDH1A1 | |
| SCHEMBL19732791 | 0.65 | IDH1 (0.44) | POLBPKMLMNAIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3272750-B1 | MORPHINAN DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2021-11-03 | — | — | EP | disclosed |