Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 5/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14877957 | 0.91 | AKR1B10 (0.55) | TDP1APPHCAR2AKR1B10AKR1B1 | |
| SCHEMBL5875714 | 0.90 | TDP1 (0.53) | TDP1ATMKDM4EAPPHCAR2 | |
| Butyl Cinnamate SCHEMBL119510 | 0.89 | APP (0.65) | TDP1ATMAPPHCAR2AKR1B10 | |
| Butyl Cinnamate SCHEMBL119511 | 0.89 | APP (0.65) | TDP1ATMAPPHCAR2AKR1B10 | |
| Butyl Cinnamate SCHEMBL5314386 | 0.89 | APP (0.65) | TDP1ATMAPPHCAR2AKR1B10 | |
| SCHEMBL30023403 | 0.87 | TSHR (0.63) | TDP1ATMKDM4EAPPHCAR2 | |
| Juarezic Acid SCHEMBL8887961 | 0.87 | TSHR (0.55) | TDP1ATMKDM4EAPPHCAR2 | |
| Juarezic Acid SCHEMBL1627203 | 0.87 | TSHR (0.55) | TDP1ATMKDM4EAPPHCAR2 | |
| SCHEMBL29975936 | 0.86 | APP (0.54) | TDP1ATMAPPHCAR2LMNA | |
| SCHEMBL22881958 | 0.85 | AKR1B10 (0.52) | TDP1APPAKR1B10AKR1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026196-B2 | Delayed-effect agronomic treatment agent, in particular for seed germination and plant development | CLAUSE (FR) | 2011-09-27 | — | — | US | claimed |
| US-20090199314-A1 | DELAYED-EFFECT AGRONOMIC TREATMENT AGENT, IN PARTICULAR FOR SEED GERMINATION AND PLANT DEVELOPMENT | CLAUSE TEZIER (FR) | 2009-08-06 | — | — | US | claimed |
| EP-4163277-B1 | NOVEL PYRAZOLE DERIVATIVES | APTABIO THERAPEUTICS INC (KR) | 2026-01-14 | — | — | EP | disclosed |
| EP-4501920-A1 | NOVEL PYRAZOLE DERIVATIVES | Aptabio Therapeutics Inc. (KR) | 2025-02-05 | — | — | EP | disclosed |
| US-20240308983-A1 | NOVEL PYRAZOLE DERIVATIVES | APTABIO THERAPEUTICS INC (KR) | 2024-09-19 | — | — | US | disclosed |
| US-11999718-B2 | Pyrazole derivatives | APTABIO THERAPEUTICS INC. (KR) | 2024-06-04 | — | — | US | disclosed |
| US-20230234940-A1 | NOVEL PYRAZOLE DERIVATIVES | APTABIO THERAPEUTICS INC. (KR) | 2023-07-27 | — | — | US | disclosed |
| EP-4163277-A1 | NOVEL PYRAZOLE DERIVATIVES | Aptabio Therapeutics Inc. (KR) | 2023-04-12 | — | — | EP | disclosed |
| CN-115073294-A | Method for synthesizing axial chiral aryl conjugated diene through asymmetric alfa-C-H olefination reaction and product thereof | 杭州师范大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-105330780-B | A kind of styrene base resin porous material of adsorbable polycyclic aromatic hydrocarbon and preparation method thereof | 同济大学 | 2018-06-05 | — | — | CN | disclosed |
| US-8026196-B2 | Delayed-effect agronomic treatment agent, in particular for seed germination and plant development | CLAUSE (FR) | 2011-09-27 | — | — | US | disclosed |
| US-20090199314-A1 | DELAYED-EFFECT AGRONOMIC TREATMENT AGENT, IN PARTICULAR FOR SEED GERMINATION AND PLANT DEVELOPMENT | CLAUSE TEZIER (FR) | 2009-08-06 | — | — | US | disclosed |
| US-20090175515-A1 | METHOD, DEVICE, AND COMPUTER PROGRAMME FOR EVALUATING IMAGES OF A CAVITY | TOMTEC IMAGING SYSTEMS GMBH (DE) | 2009-07-09 | — | — | US | disclosed |
| US-5356660-A | Method for obtaining composite conductive materials based on conductive polymers, with controlled dielectrical properties | THOMSON-CSF (FR) | 1994-10-18 | — | — | US | disclosed |
| US-5104580-A | CONDUCTIVE COMPOSITE POLYMER FILM AND METHOD FOR ITS MANUFACTURE | THOMSON-CSF (FR) | 1992-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11999718-B2 | Pyrazole derivatives | CYP11B1, CYP11B2, CYP3A43 | TDP1 1482/4885ATM 3063/4885KDM4E 3939/4885 |
| US-20230234940-A1 | NOVEL PYRAZOLE DERIVATIVES | CYP4B1, CYP3A43, CYP11B1 | TDP1 1501/4885ATM 2945/4885KDM4E 4060/4885 |
| US-20240308983-A1 | NOVEL PYRAZOLE DERIVATIVES | CYP4B1, CYP3A43, CYP11B1 | TDP1 1501/4885ATM 2945/4885KDM4E 4060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.