SCHEMBL5875714

SCHEMBL5875714

CCCCC=CC(=O)O.CCCCOC(=O)C=CC=Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.53
HCAR2 Q8TDS4 3/20 0.50
APP P05067 5/20 0.48
KDM4E B2RXH2 2/20 0.47
ATM Q13315 1/20 0.44
AKR1B10 O60218 1/20 0.44
AKR1B1 P15121 1/20 0.44
MAPT P10636 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2396951 0.90 TDP1 (0.59) TDP1HCAR2APPKDM4EATM
SCHEMBL6676460 0.85 TDP1 (0.41) TDP1HCAR2KDM4EMAPTMEN1
Juarezic Acid SCHEMBL8887961 0.83 TSHR (0.55) TDP1HCAR2APPKDM4EATM
Juarezic Acid SCHEMBL1627203 0.83 TSHR (0.55) TDP1HCAR2APPKDM4EATM
SCHEMBL14877957 0.82 AKR1B10 (0.55) TDP1HCAR2APPAKR1B10AKR1B1
Butyl Cinnamate SCHEMBL119511 0.80 APP (0.65) TDP1HCAR2APPATMAKR1B10
Butyl Cinnamate SCHEMBL119510 0.80 APP (0.65) TDP1HCAR2APPATMAKR1B10
Butyl Cinnamate SCHEMBL5314386 0.80 APP (0.65) TDP1HCAR2APPATMAKR1B10
SCHEMBL20358113 0.80 AKR1B10 (0.57) TDP1HCAR2APPAKR1B10AKR1B1
SCHEMBL20358112 0.80 AKR1B10 (0.57) TDP1HCAR2APPAKR1B10AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815498-B2 BLOCK POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2004-11-09 US claimed
EP-1252203-B1 METHOD FOR PRODUCING A POLYMERIC CONVERSION PRODUCT BASF AG (DE) 2004-03-17 EP claimed
US-20030018137-A1 Method for producing a polymeric conversion product BASF AKTIENGESELLSCHAFT (DE) 2003-01-23 US claimed
US-7008990-B2 Use of polymeric reaction product BASF AKTIENGESELLSCHAFT (DE) 2006-03-07 US disclosed
US-6815498-B2 BLOCK POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2004-11-09 US disclosed
US-20040034182-A1 Method for the production of a polymerisation reaction product BASF AKTIENGESELLSCHAFT (DE) 2004-02-19 US disclosed
US-20040014872-A1 Bonding agent composition containing solid matter, with radically polymerised block copolymers BASF AKTIENGESELLSCHAFT (DE) 2004-01-22 US disclosed
US-20030170306-A1 Use of polymeric reaction product BASF AKTIENGESELLSCHAFT (DE) 2003-09-11 US disclosed
US-20030018137-A1 Method for producing a polymeric conversion product BASF AKTIENGESELLSCHAFT (DE) 2003-01-23 US disclosed
US-6506836-B1 Reacting under free-radical conditions a reaction mixture comprising at least one free-radically reactable monomer (a) in the presence of at least one free-radical initiator and of a compound process for preparing a polymer using said reaction BASF AKTIENGESELLSCHAFT (DE) 2003-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030170306-A1 Use of polymeric reaction product OXSR1, OGFR, CBR1 TDP1 4722/4885HCAR2 651/4885APP 3765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.