SCHEMBL23969583

SCHEMBL23969583

COC(=O)CCCCC(=O)ON1C(=O)c2ccccc2C1=O

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 3/20 0.47
PTPN13 Q12923 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
HSD17B10 Q99714 1/20 0.47
ALDH1A1 P00352 1/20 0.44
MAPT P10636 1/20 0.44
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
TNF P01375 1/20 0.43
PDE4A P27815 1/20 0.43
PDE4B Q07343 1/20 0.43
PDE4C Q08493 1/20 0.43
PDE4D Q08499 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5350218 0.97 PTPRC (0.48) PTPRCPTPN13MEN1KMT2AHSD17B10
SCHEMBL5351912 0.94 ALDH1A1 (0.47) PTPRCPTPN13MEN1KMT2AHSD17B10
SCHEMBL28693655 0.92 ALDH1A1 (0.47) MEN1KMT2AHSD17B10ALDH1A1MAPT
SCHEMBL30731584 0.90 ALDH1A1 (0.47) MEN1KMT2AHSD17B10ALDH1A1MAPT
SCHEMBL23969638 0.90 ALDH1A1 (0.47) MEN1KMT2AHSD17B10ALDH1A1MAPT
SCHEMBL3676598 0.88 ASAH1 (0.48) MEN1KMT2AHSD17B10ALDH1A1MAPT
SCHEMBL3678799 0.86 ASAH1 (0.50) MEN1KMT2AHSD17B10ALDH1A1
SCHEMBL3678825 0.86 ASAH1 (0.50) MEN1KMT2AHSD17B10ALDH1A1
SCHEMBL3679722 0.86 ASAH1 (0.50) MEN1KMT2AHSD17B10ALDH1A1
SCHEMBL1537374 0.86 ASAH1 (0.50) MEN1KMT2AHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220024949-A1 CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS THE SCRIPPS RESEARCH INSTITUTE 2022-01-27 US disclosed
US-11161859-B2 Cu- and Ni-catalyzed decarboxylative borylation reactions THE SCRIPPS RESEARCH INSTITUTE (US) 2021-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11161859-B2 Cu- and Ni-catalyzed decarboxylative borylation reactions PCSK9, LIPA, ACSL3 PTPRC 3161/4885PTPN13 3614/4885MEN1 2765/4885
US-20220024949-A1 CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS PCSK9, PCSK7, PCSK6 PTPRC 3434/4885PTPN13 3823/4885MEN1 2960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.