Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969551 | 0.84 | LMNA (0.44) | PTGS2PTGS1PGRLMNACYP2C9 | |
| SCHEMBL30731578 | 0.84 | LMNA (0.44) | PTGS2PTGS1PGRLMNACYP2C9 | |
| SCHEMBL5540417 | 0.83 | PTGS2 (0.55) | PTGS2PTGS1PGRADORA3SLC6A2 | |
| SCHEMBL577384 | 0.82 | PTGS2 (0.63) | PTGS2PTGS1PGRADORA3SLC6A2 | |
| SCHEMBL26018580 | 0.81 | PTGS2 (0.53) | PTGS2PTGS1PGRADORA3SLC6A2 | |
| SCHEMBL10085431 | 0.81 | PTGS2 (0.53) | PTGS2PTGS1PGRADORA3SLC6A2 | |
| SCHEMBL5539028 | 0.79 | PTGS1 (0.55) | PTGS2PTGS1PGRADORA3SLC6A2 | |
| SCHEMBL5540399 | 0.77 | PTGS1 (0.53) | PTGS2PTGS1PGRADORA3SLC6A2 | |
| SCHEMBL576679 | 0.77 | PTGS2 (0.57) | PTGS2PTGS1PGRADORA3SLC6A2 | |
| SCHEMBL576871 | 0.76 | CHRM1 (0.57) | PTGS2PTGS1CXCR1CXCR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110799193-B | Copper and nickel catalyzed decarboxylation borylation | 斯克利普斯研究院 | 2023-12-12 | — | — | CN | disclosed |
| US-20220024949-A1 | CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS | THE SCRIPPS RESEARCH INSTITUTE | 2022-01-27 | — | — | US | disclosed |
| US-11161859-B2 | Cu- and Ni-catalyzed decarboxylative borylation reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-11-02 | — | — | US | disclosed |
| CN-110799193-A | Copper and nickel catalyzed decarboxylation and boriding reactions | 斯克利普斯研究院 | 2020-02-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161859-B2 | Cu- and Ni-catalyzed decarboxylative borylation reactions | PCSK9, LIPA, ACSL3 | PTGS2 4140/4885PTGS1 3809/4885PGR 394/4885 |
| US-20220024949-A1 | CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS | PCSK9, PCSK7, PCSK6 | PTGS2 3958/4885PTGS1 3762/4885PGR 434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.