Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CDC42 | P60953 | 1/20 | 0.56 |
| ▸ | RAC1 | P63000 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL219579 | 1.00 | TDP1 (0.59) | TDP1L3MBTL1PTGS2PTGS1AKR1C3 | |
| SCHEMBL5538883 | 0.83 | PTGS2 (0.57) | TDP1L3MBTL1PTGS2PTGS1AKR1C3 | |
| SCHEMBL2425993 | 0.82 | TDP1 (0.61) | TDP1L3MBTL1PTGS2PTGS1AKR1C3 | |
| SCHEMBL9652335 | 0.82 | TDP1 (0.61) | TDP1L3MBTL1PTGS2PTGS1AKR1C3 | |
| SCHEMBL5535859 | 0.81 | PTGS2 (0.66) | TDP1L3MBTL1PTGS2PTGS1AKR1C3 | |
| SCHEMBL577152 | 0.80 | PTGS2 (0.54) | TDP1L3MBTL1PTGS2PTGS1AKR1C3 | |
| SCHEMBL30731578 | 0.79 | LMNA (0.44) | PTGS2PTGS1CYP1A2LMNACYP2C9 | |
| SCHEMBL23969551 | 0.79 | LMNA (0.44) | PTGS2PTGS1CYP1A2LMNACYP2C9 | |
| SCHEMBL5539984 | 0.78 | PTGS2 (0.54) | TDP1L3MBTL1PTGS2PTGS1AKR1C3 | |
| SCHEMBL5540261 | 0.78 | PTGS2 (0.54) | TDP1L3MBTL1PTGS2PTGS1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110799193-B | Copper and nickel catalyzed decarboxylation borylation | 斯克利普斯研究院 | 2023-12-12 | — | — | CN | disclosed |
| US-20220024949-A1 | CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS | THE SCRIPPS RESEARCH INSTITUTE | 2022-01-27 | — | — | US | disclosed |
| US-11161859-B2 | Cu- and Ni-catalyzed decarboxylative borylation reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-11-02 | — | — | US | disclosed |
| CN-110799193-A | Copper and nickel catalyzed decarboxylation and boriding reactions | 斯克利普斯研究院 | 2020-02-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161859-B2 | Cu- and Ni-catalyzed decarboxylative borylation reactions | PCSK9, LIPA, ACSL3 | TDP1 4278/4885L3MBTL1 1674/4885PTGS2 4140/4885 |
| US-20220024949-A1 | CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS | PCSK9, PCSK7, PCSK6 | TDP1 4230/4885L3MBTL1 3137/4885PTGS2 3958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.