Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CES1 | P23141 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12963614 | 0.78 | TDP1 (0.45) | ALDH1A1MAPK1TDP1TSHRMEN1 | |
| SCHEMBL23019643 | 0.74 | TDP1 (0.41) | ALDH1A1MAPK1TDP1TSHRMEN1 | |
| SCHEMBL4536997 | 0.71 | TDP1 (0.45) | ALDH1A1MAPK1TDP1TSHRMEN1 | |
| SCHEMBL4536988 | 0.71 | TDP1 (0.45) | ALDH1A1MAPK1TDP1TSHRMEN1 | |
| SCHEMBL19624772 | 0.71 | AKT1 (0.39) | ALDH1A1MAPK1TDP1TSHRMEN1 | |
| SCHEMBL4536993 | 0.71 | TDP1 (0.45) | ALDH1A1MAPK1TDP1TSHRMEN1 | |
| SCHEMBL10228486 | 0.71 | TDP1 (0.35) | ALDH1A1MAPK1TDP1TSHRMEN1 | |
| SCHEMBL13066991 | 0.69 | TDP1 (0.41) | ALDH1A1MAPK1TDP1TSHRMEN1 | |
| SCHEMBL21659115 | 0.69 | MTNR1A (0.44) | ALDH1A1MAPK1TDP1TSHRMEN1 | |
| SCHEMBL23969673 | 0.69 | ATM (0.37) | ALDH1A1MAPK1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904366-A1 | END CAPPED NUCLEIC ACID MOLECULES | Novartis AG (CH) | 2021-11-03 | — | — | EP | disclosed |