Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969709 | 0.81 | ATM (0.35) | ATMTDP1MTNR1AMTNR1BGAA | |
| SCHEMBL23969805 | 0.81 | CES1 (0.37) | ATMCES1CES2TDP1MTNR1A | |
| SCHEMBL23969741 | 0.78 | AKT1 (0.35) | ATMCES1CES2ALDH1A1HPGD | |
| SCHEMBL22037150 | 0.78 | ERCC5 (0.36) | GAAALDH1A1HPGDRAB9AMAPK1 | |
| SCHEMBL25840238 | 0.78 | ERCC5 (0.36) | GAAALDH1A1HPGDRAB9AMAPK1 | |
| SCHEMBL10228486 | 0.73 | TDP1 (0.35) | CES1CES2TDP1GAANPSR1 | |
| SCHEMBL12963614 | 0.73 | TDP1 (0.45) | ATMCES1CES2TDP1MTNR1A | |
| SCHEMBL19624772 | 0.73 | AKT1 (0.39) | CES1CES2TDP1GAANPSR1 | |
| SCHEMBL20305986 | 0.73 | MTNR1A (0.38) | ATMCES1CES2TDP1MTNR1A | |
| SCHEMBL13066991 | 0.72 | TDP1 (0.41) | CES1CES2TDP1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904366-A1 | END CAPPED NUCLEIC ACID MOLECULES | Novartis AG (CH) | 2021-11-03 | — | — | EP | disclosed |