Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24181363 | 0.80 | NPC1 (0.35) | NPC1GAAMAPK1RAB9A | |
| SCHEMBL2463655 | 0.78 | ALDH1A1 (0.43) | COMTNPC1GAAMAPK1RAB9A | |
| SCHEMBL27509597 | 0.74 | MAPT (0.39) | COMTNPC1GAAMAPK1RAB9A | |
| SCHEMBL23874485 | 0.74 | LMNA (0.31) | COMT | |
| SCHEMBL16809381 | 0.72 | NPC1 (0.32) | NPC1GAAMAPK1RAB9A | |
| SCHEMBL115387 | 0.69 | — | — | |
| SCHEMBL15796727 | 0.67 | COMT (0.42) | COMTNPC1GAAMAPK1RAB9A | |
| Ammonia Solution, Strong SCHEMBL4486064 | 0.67 | NOS1 (0.42) | COMTNPC1GAAMAPK1RAB9A | |
| SCHEMBL12251583 | 0.67 | KMT2A (0.48) | COMTNPC1GAAMAPK1RAB9A | |
| SCHEMBL27533523 | 0.67 | COMT (0.39) | COMTNPC1GAAMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904366-A1 | END CAPPED NUCLEIC ACID MOLECULES | Novartis AG (CH) | 2021-11-03 | — | — | EP | disclosed |