Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4K2A | Q9BTU6 | 6/20 | 0.56 |
| ▸ | PI4KA | P42356 | 5/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 5/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | AHCY | P23526 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.44 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27438888 | 0.76 | PI4KA (0.67) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL6045856 | 0.73 | PI4K2A (0.49) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL6045694 | 0.73 | PI4K2A (0.49) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL21311217 | 0.73 | ADORA2A (0.47) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL9687595 | 0.72 | PI4KA (0.54) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL9687602 | 0.72 | PI4KA (0.54) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL21311216 | 0.71 | ADORA2A (0.47) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL25521510 | 0.71 | ADORA3 (0.53) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL23025515 | 0.71 | ADORA3 (0.53) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL8094883 | 0.71 | ADORA2A (0.50) | PI4K2API4KAPI4K2BPI4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904366-A1 | END CAPPED NUCLEIC ACID MOLECULES | Novartis AG (CH) | 2021-11-03 | — | — | EP | disclosed |