Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 6/20 | 0.54 |
| ▸ | PI4K2B | Q8TCG2 | 6/20 | 0.54 |
| ▸ | PI4K2A | Q9BTU6 | 6/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.54 |
| ▸ | GMPS | P49915 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AHCY | P23526 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687595 | 1.00 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBGMPS | |
| SCHEMBL27438888 | 0.77 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBGMPS | |
| SCHEMBL23969763 | 0.72 | PI4K2A (0.56) | PI4KAPI4K2BPI4K2API4KBGMPS | |
| SCHEMBL31256605 | 0.70 | GMPS (0.56) | PI4KAPI4K2BPI4K2API4KBGMPS | |
| SCHEMBL9397052 | 0.69 | PI4K2A (0.59) | PI4KAPI4K2BPI4K2API4KBGMPS | |
| SCHEMBL10650083 | 0.69 | PI4KA (0.59) | PI4KAPI4K2BPI4K2API4KBGMPS | |
| SCHEMBL10517348 | 0.69 | ADORA2A (0.47) | PI4KAPI4K2BPI4K2API4KBGMPS | |
| SCHEMBL10517351 | 0.69 | ADORA2A (0.47) | PI4KAPI4K2BPI4K2API4KBGMPS | |
| SCHEMBL7738504 | 0.69 | PI4KA (0.66) | PI4KAPI4K2BPI4K2API4KBGMPS | |
| SCHEMBL10649999 | 0.68 | PI4K2A (0.51) | PI4KAPI4K2BPI4K2API4KBGMPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155112-A | Antiviral agents; Herpes virus | GLAXO GROUP LIMITED (GB) | 1992-10-13 | — | — | US | disclosed |
| EP-0430518-A2 | Cyclopentane derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-05 | — | — | EP | disclosed |