Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | XIAP | P98170 | 1/20 | 0.57 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.57 |
| ▸ | CPA1 | P15085 | 4/20 | 0.53 |
| ▸ | CPA3 | P15088 | 3/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | CPB1 | P15086 | 1/20 | 0.53 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.53 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7483692 | 1.00 | CYP1A2 (0.61) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL1566396 | 1.00 | CYP1A2 (0.61) | CYP1A2ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL6054521 | 0.98 | CYP1A2 (0.59) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL6958621 | 0.86 | CYP1A2 (0.56) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL6054519 | 0.84 | CYP1A2 (0.54) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL11859970 | 0.84 | CYP1A2 (0.54) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL11663421 | 0.83 | PPARG (0.65) | CYP1A2PTGS1PPARGPPARA | |
| SCHEMBL133927 | 0.83 | PPARG (0.56) | PPARGPPARA | |
| SCHEMBL4803142 | 0.83 | SLC7A5 (0.60) | SLC7A5FOLH1 | |
| SCHEMBL5763729 | 0.83 | EPHX1 (0.58) | CYP1A2ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130274470-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-10-17 | — | — | US | disclosed |
| US-20130274470-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-10-17 | — | — | US | disclosed |
| US-20130274470-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-10-17 | — | — | US | disclosed |
| US-20110224431-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-09-15 | — | — | US | disclosed |
| US-20110224431-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-09-15 | — | — | US | disclosed |
| US-20060247470-A1 | Process for producing optically active carboxylic acid substituted in 2-position | KANEKA CORPORATION | 2006-11-02 | — | — | US | disclosed |
| US-7094926-B2 | Process for producing optically active carboxylic acid substituted in 2-position | KANEKA CORPORATION (JP) | 2006-08-22 | — | — | US | disclosed |
| US-20030144546-A1 | Process for producing optically active carboxylic acid subtituted in 2-position | KANEKA CORPORATION (JP) | 2003-07-31 | — | — | US | disclosed |
| US-20030013903-A1 | Process for crystallization of 2-acetylthio-3-phenyl-propionic acid | KANEKA CORPORATION (JP) | 2003-01-16 | — | — | US | disclosed |
| EP-1275642-A1 | PROCESS FOR CRYSTALLIZATION OF 2-ACETYLTHIO-3-PHENYL-PROPIONIC ACID | KANEKA CORPORATION (JP) | 2003-01-15 | — | — | EP | disclosed |
| EP-1251115-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID SUBSTITUTED IN 2-POSITION | KANEKA CORPORATION (JP) | 2002-10-23 | — | — | EP | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274470-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | HDHD5, DCX, CLK2 | CYP1A2 1524/4885ALPI 4763/4885PKM 3559/4885 |
| US-20030144546-A1 | Process for producing optically active carboxylic acid subtituted in 2-position | HAO2, CA2, HACL2 | CYP1A2 1015/4885ALPI 1743/4885PKM 3646/4885 |
| US-20110224431-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | HDHD5, DCX, CLK2 | CYP1A2 1524/4885ALPI 4763/4885PKM 3559/4885 |
| US-20060247470-A1 | Process for producing optically active carboxylic acid substituted in 2-position | HAO2, CA2, HACL2 | CYP1A2 603/4885ALPI 969/4885PKM 3421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.