SCHEMBL23972104

SCHEMBL23972104

CNC(=O)C(NOC)c1cccc(C)c1CO/N=C(\C)c1ccccc1COC

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.33
PRMT5 O14744 1/20 0.30
NR1H4 Q96RI1 1/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23986569 0.91 CXCR5 (0.32) HIF1A
SCHEMBL23979025 0.88
SCHEMBL23971905 0.88 KCNK3 (0.38)
SCHEMBL26501104 0.85
SCHEMBL25721637 0.85 PPARG (0.31) LMNA
SCHEMBL25723482 0.85 CES2 (0.32)
SCHEMBL23986501 0.85 KMT2A (0.37)
SCHEMBL25721765 0.85 CNR2 (0.33) NR1H4
SCHEMBL25665274 0.84 CTSV (0.32) SMN1; SMN2
SCHEMBL23984177 0.84 P2RX7 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021219387-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS II BASF SE (DE) 2021-11-04 WO disclosed