Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 9/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 7/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30229440 | 1.00 | HTR3E (0.38) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL30305704 | 1.00 | HTR3E (0.38) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL30229698 | 0.79 | RIPK1 (0.43) | GHSRL3MBTL1ALDH1A1 | |
| SCHEMBL30305700 | 0.79 | RIPK1 (0.43) | GHSRL3MBTL1ALDH1A1 | |
| SCHEMBL22112279 | 0.73 | GRIK1 (0.45) | GRIK1 | |
| SCHEMBL22091607 | 0.73 | GRIK1 (0.45) | GRIK1 | |
| SCHEMBL28783783 | 0.72 | HTR3E (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29116646 | 0.72 | DPP8 (0.38) | HDAC2KDM4EALDH1A1 | |
| SCHEMBL21246188 | 0.69 | CYP2D6 (0.52) | KDM4E | |
| SCHEMBL1527359 | 0.69 | CYP2D6 (0.52) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219661-A1 | ALKYLAMINOPROLINE DERIVATIVES AS ALFA-2-DELTA-1 BLOCKERS | ACONDICIONAMIENTO TARRASENSE (ES) | 2021-11-04 | — | — | WO | disclosed |
| EP-3904339-A1 | ALKYLAMINOPROLINE DERIVATIVES AS ALFA-2-DELTA-1 BLOCKERS | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-11-03 | — | — | EP | disclosed |