Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30305700 | 1.00 | RIPK1 (0.43) | RIPK1DPP4TACR1DPP8DPP7 | |
| SCHEMBL23992516 | 0.86 | DPP8 (0.52) | DPP4DPP8DPP7NPC1 | |
| SCHEMBL30229518 | 0.86 | DPP8 (0.52) | DPP4DPP8DPP7NPC1 | |
| SCHEMBL30229541 | 0.82 | DPP4 (0.45) | RIPK1DPP4DPP8DPP7CCR5 | |
| SCHEMBL23992599 | 0.82 | DPP4 (0.45) | RIPK1DPP4DPP8DPP7CCR5 | |
| SCHEMBL23972746 | 0.79 | HTR3E (0.38) | ALDH1A1GHSRL3MBTL1 | |
| SCHEMBL30305704 | 0.79 | HTR3E (0.38) | ALDH1A1GHSRL3MBTL1 | |
| SCHEMBL30229440 | 0.79 | HTR3E (0.38) | ALDH1A1GHSRL3MBTL1 | |
| SCHEMBL30229534 | 0.78 | DPP4 (0.50) | RIPK1DPP4DPP8DPP7ALDH1A1 | |
| SCHEMBL30305702 | 0.78 | DPP4 (0.50) | RIPK1DPP4DPP8DPP7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115702142-A | Alkylaminoproline derivatives as alpha-2-delta-1 blockers | 塔拉森斯调节公司 | 2023-02-14 | — | — | CN | claimed |
| US-11905243-B2 | Alkylaminoproline derivatives as alpha-2-delta-1 blockers | ACONDICIONAMIENTO TARRASENSE (ES) | 2024-02-20 | — | — | US | disclosed |
| US-20230100599-A1 | Alkylaminoproline Derivatives as alpha-2-delta-1 Blockers | ACONDICIONAMIENTO TARRASENSE (ES) | 2023-03-30 | — | — | US | disclosed |
| CN-115702142-A | Alkylaminoproline derivatives as alpha-2-delta-1 blockers | 塔拉森斯调节公司 | 2023-02-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230100599-A1 | Alkylaminoproline Derivatives as alpha-2-delta-1 Blockers | CACNG2, CACNA1B, CACNA1C | RIPK1 3531/4885DPP4 1427/4885TACR1 1056/4885 |
| US-11905243-B2 | Alkylaminoproline derivatives as alpha-2-delta-1 blockers | CACNG2, CACNA1B, CACNA1C | RIPK1 3531/4885DPP4 1427/4885TACR1 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.