Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22016792 | 0.86 | CTSL (0.47) | CTSLCTSSCTSKCTSBTSHR | |
| SCHEMBL14268037 | 0.86 | CTSL (0.47) | CTSLCTSSCTSKCTSBTSHR | |
| SCHEMBL22016896 | 0.86 | CTSL (0.47) | CTSLCTSSCTSKCTSBTSHR | |
| SCHEMBL14450112 | 0.85 | TSHR (0.40) | CTSLCTSSCTSKTACR3LMNA | |
| SCHEMBL1421212 | 0.85 | OPRK1 (0.45) | CTSLCTSSCTSKTACR3LMNA | |
| SCHEMBL12797626 | 0.85 | OPRK1 (0.45) | CTSLCTSSCTSKTACR3LMNA | |
| SCHEMBL1456364 | 0.84 | SIGMAR1 (0.48) | CTSLCTSSCTSKLMNA | |
| SCHEMBL8869767 | 0.84 | SIGMAR1 (0.48) | CTSLCTSSCTSKLMNA | |
| SCHEMBL24170304 | 0.83 | CTSL (0.38) | CTSLCTSSCTSKTACR3LMNA | |
| SCHEMBL10831305 | 0.83 | AOC3 (0.42) | CTSLCTSSCTSKTACR3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026218-B2 | Bifunctional analgesic compounds for opioid receptor agonists and neurokinin-1 receptor antagonists | THE UNIVERSITY OF ARIZONA (US) | 2011-09-27 | — | — | US | claimed |
| EP-1670446-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2006-06-21 | — | — | EP | claimed |
| WO-2005030185-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | WO | claimed |
| US-8026218-B2 | Bifunctional analgesic compounds for opioid receptor agonists and neurokinin-1 receptor antagonists | THE UNIVERSITY OF ARIZONA (US) | 2011-09-27 | — | — | US | disclosed |
| US-20080039404-A1 | BIFUNCTIONAL ANALGESIC COMPOUNDS FOR OPIOID RECEPTOR AGONISTS AND NEUROKININ-1 RECEPTOR ANTAGONISTS | UNIVERSITY OF ARIZONA (US) | 2008-02-14 | — | — | US | disclosed |
| EP-1670446-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005030185-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | WO | disclosed |