Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22299956 | 0.91 | FOLH1 (0.38) | FOLH1MAPK1MEN1KMT2ATSHR | |
| SCHEMBL24491154 | 0.79 | FOLH1 (0.38) | FOLH1MAPK1MAPTCA12CA1 | |
| SCHEMBL23974075 | 0.77 | FOLH1 (0.35) | FOLH1CA2OPRM1F2RL1 | |
| SCHEMBL24491200 | 0.77 | FOLH1 (0.36) | FOLH1MAPK1KMT2ANPC1RAB9A | |
| SCHEMBL23974353 | 0.76 | FOLH1 (0.43) | FOLH1MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL22299551 | 0.76 | FOLH1 (0.39) | FOLH1CA12CA1CA2CA9 | |
| SCHEMBL24451215 | 0.76 | DGAT1 (0.34) | FOLH1 | |
| SCHEMBL26770669 | 0.73 | MTNR1A (0.37) | FOLH1MAPK1MEN1KMT2ATSHR | |
| SCHEMBL22541244 | 0.73 | FOLH1 (0.34) | FOLH1KITPDGFRAOPRM1OPRD1 | |
| SCHEMBL26032229 | 0.71 | GLP1R (0.39) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903825-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | Coherent Biopharma (Suzhou), Limited (CN) | 2021-11-03 | — | — | EP | disclosed |