Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23974348 | 0.80 | OPRM1 (0.35) | FOLH1OPRM1OPRD1OPRK1DGAT1 | |
| SCHEMBL22300339 | 0.79 | GBA1 (0.36) | FOLH1OPRM1OPRD1OPRK1DGAT1 | |
| SCHEMBL23974239 | 0.78 | OPRM1 (0.38) | FOLH1OPRM1OPRD1OPRK1DGAT1 | |
| SCHEMBL23974072 | 0.76 | FOLH1 (0.41) | FOLH1MAPK1OPRM1OPRD1OPRK1 | |
| SCHEMBL24491154 | 0.76 | FOLH1 (0.38) | FOLH1MAPK1CA12CA1CA2 | |
| SCHEMBL24491200 | 0.76 | FOLH1 (0.36) | FOLH1MAPK1RAB9ANPC1CA12 | |
| SCHEMBL22299956 | 0.74 | FOLH1 (0.38) | FOLH1MAPK1OPRM1OPRD1OPRK1 | |
| SCHEMBL2358722 | 0.73 | GBA1 (0.38) | OPRM1OPRD1OPRK1DGAT1F2RL1 | |
| SCHEMBL12342507 | 0.73 | TTR (0.51) | FOLH1MAPK1MGAMOPRM1RAB9A | |
| SCHEMBL12342495 | 0.72 | TTR (0.42) | FOLH1MAPK1MGAMOPRM1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903825-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | Coherent Biopharma (Suzhou), Limited (CN) | 2021-11-03 | — | — | EP | disclosed |