Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | MAP1B | P46821 | 1/20 | 0.32 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | PLK1 | P53350 | 2/20 | 0.32 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | GNRHR | P30968 | 5/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23974353 | 0.78 | FOLH1 (0.43) | OPRM1FOLH1F2RL1DGAT1OPRD1 | |
| SCHEMBL22299551 | 0.73 | FOLH1 (0.39) | OPRM1FOLH1SIRT2HDAC3HDAC1 | |
| SCHEMBL24491189 | 0.72 | OPRM1 (0.38) | OPRM1FOLH1SIRT2HDAC3HDAC1 | |
| SCHEMBL24491155 | 0.71 | OPRM1 (0.37) | OPRM1FOLH1SIRT2HDAC3HDAC1 | |
| SCHEMBL23974243 | 0.70 | OPRM1 (0.36) | OPRM1FOLH1SIRT2HDAC3HDAC1 | |
| SCHEMBL22299572 | 0.69 | OPRM1 (0.37) | OPRM1FOLH1SIRT2HDAC3HDAC1 | |
| SCHEMBL22299956 | 0.68 | FOLH1 (0.38) | OPRM1FOLH1F2RL1OPRD1OPRK1 | |
| SCHEMBL23974072 | 0.66 | FOLH1 (0.41) | OPRM1FOLH1F2RL1OPRD1OPRK1 | |
| SCHEMBL24491154 | 0.66 | FOLH1 (0.38) | FOLH1 | |
| SCHEMBL24491200 | 0.64 | FOLH1 (0.36) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903825-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | Coherent Biopharma (Suzhou), Limited (CN) | 2021-11-03 | — | — | EP | disclosed |