Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18958983 | 0.75 | TSHR (0.37) | TSHRMEN1KMT2AADRA1APDE4D | |
| SCHEMBL20143799 | 0.74 | — | — | |
| SCHEMBL24799302 | 0.73 | TSHR (0.36) | TSHRMEN1KMT2AADRA1A | |
| SCHEMBL27869319 | 0.69 | TSHR (0.43) | TSHRMEN1KMT2AADRA1APDE4D | |
| SCHEMBL22013342 | 0.69 | GRM4 (0.31) | — | |
| SCHEMBL4678096 | 0.69 | TSHR (0.43) | TSHRMEN1KMT2AADRA1APDE4D | |
| SCHEMBL22832226 | 0.69 | LMNA (0.43) | TSHRMEN1KMT2A | |
| SCHEMBL28707591 | 0.69 | LMNA (0.43) | TSHRMEN1KMT2A | |
| SCHEMBL2478389 | 0.69 | TSHR (0.48) | TSHRMEN1KMT2AADRA1APDE4D | |
| SCHEMBL12120664 | 0.69 | TSHR (0.39) | TSHRMEN1KMT2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338834-A1 | DEGRADABLE HYALURONIC ACID HYDROGELS | ASCENDIS PHARMA A/S (DK) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338834-A1 | DEGRADABLE HYALURONIC ACID HYDROGELS | CD44, HPSE, MMP13 | TSHR 1264/4885MEN1 2545/4885KMT2A 1851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.