Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB3 | Q13509 | 4/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30484199 | 0.93 | TUBB3 (0.38) | TUBB3ABCB1CCR1CCR5CCR8 | |
| SCHEMBL23975862 | 0.93 | TUBB3 (0.38) | TUBB3ABCB1CCR1CCR5CCR8 | |
| SCHEMBL30225209 | 0.92 | SPR (0.39) | TUBB3ABCB1CCR1CCR5CCR8 | |
| SCHEMBL23975838 | 0.92 | SPR (0.39) | TUBB3ABCB1CCR1CCR5CCR8 | |
| SCHEMBL23976283 | 0.91 | ABCB1 (0.38) | TUBB3ABCB1CCR1CCR5CCR8 | |
| SCHEMBL30118610 | 0.91 | ABCB1 (0.38) | TUBB3ABCB1CCR1CCR5CCR8 | |
| SCHEMBL23975859 | 0.89 | HDAC1 (0.39) | TUBB3ABCB1CCR1CCR5CCR8 | |
| SCHEMBL30225179 | 0.88 | ABCB1 (0.39) | TUBB3ABCB1CCR1CCR5CCR8 | |
| SCHEMBL23975852 | 0.88 | ABCB1 (0.39) | TUBB3ABCB1CCR1CCR5CCR8 | |
| SCHEMBL23976102 | 0.88 | SPR (0.38) | TUBB3ABCB1CCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222483-A1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |