Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | C5AR1 | P21730 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12201360 | 0.85 | GAA (0.59) | GAANPSR1ALDH1A1HTTMAPT | |
| SCHEMBL28002534 | 0.81 | KMT2A (0.66) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL25221412 | 0.81 | GAA (0.76) | GAANPSR1ALDH1A1HTTMAPT | |
| Hydrochloric Acid SCHEMBL30004917 | 0.80 | KMT2A (0.64) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30006002 | 0.80 | KMT2A (0.64) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL25218568 | 0.78 | ALDH1A1 (0.58) | GAANPSR1ALDH1A1HTTMAPT | |
| SCHEMBL6467738 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3351370 | 0.76 | KMT2A (0.44) | GAANPSR1ALDH1A1MAPTMEN1 | |
| SCHEMBL2762268 | 0.76 | MAPT (0.46) | GAANPSR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3260769 | 0.76 | C5AR1 (0.58) | GAANPSR1ALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212974-A1 | METHOD FOR IDENTIFYING COMPOUNDS USEFUL FOR TREATING AND/OR PREVENTING DISEASE-ASSOCIATED BONE LOSS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212974-A1 | METHOD FOR IDENTIFYING COMPOUNDS USEFUL FOR TREATING AND/OR PREVENTING DISEASE-ASSOCIATED BONE LOSS | DOCK5, ARHGDIB, ARHGDIA | GAA 2337/4885NPSR1 4672/4885ALDH1A1 3992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.