Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY8 | P40145 | 3/20 | 0.51 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.51 |
| ▸ | RXRA | P19793 | 5/20 | 0.50 |
| ▸ | RXRB | P28702 | 5/20 | 0.50 |
| ▸ | RXRG | P48443 | 4/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21462308 | 0.81 | RXRA (0.70) | RXRARXRBRXRGP2RY14 | |
| SCHEMBL14214023 | 0.81 | CES2 (0.47) | ADCY8ADCY1KDM4EHTTRXFP1 | |
| SCHEMBL1004777 | 0.81 | CES2 (0.59) | KDM4EHTTHDAC6 | |
| SCHEMBL5428269 | 0.77 | HDAC6 (0.56) | P2RY14HTTNPC1HPGDRAB9A | |
| SCHEMBL25795128 | 0.76 | AKT1 (0.50) | ADCY8ADCY1HTTRAB9AHDAC6 | |
| SCHEMBL19331992 | 0.75 | RXRA (0.57) | RXRARXRBRXRGKDM4ENPC1 | |
| SCHEMBL23888875 | 0.75 | KIF11 (0.57) | RXRARXRBRXRGHDAC4HDAC6 | |
| SCHEMBL2456614 | 0.74 | GAA (0.50) | NPC1RAB9AHDAC6 | |
| SCHEMBL29889675 | 0.74 | GAA (0.50) | NPC1RAB9AHDAC6 | |
| SCHEMBL13404435 | 0.74 | RXRA (0.44) | ADCY8ADCY1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904349-A2 | N-(CYCLOPROPYLMETHYL)-5-(METHYLSULFONYL)-N-{1-[1-(PYRIMIDIN-2-YL)-1H-1,2,4-TRIAZOL-5-YL]ETHYL}HETEROCYCLYL AMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-11-03 | — | — | EP | disclosed |