Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 3/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29639686 | 0.77 | TPMT (0.50) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL22926217 | 0.77 | TPMT (0.50) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL21486502 | 0.76 | OPRM1 (0.38) | RAB9AMCHR1MEN1KMT2ANPC1 | |
| SCHEMBL23976730 | 0.76 | PARP1 (0.39) | RAB9AKCNH2MEN1KMT2ANPC1 | |
| SCHEMBL21462335 | 0.75 | RAPGEF3 (0.41) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL29672156 | 0.75 | RAPGEF3 (0.41) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL21484194 | 0.73 | GRN (0.37) | RAB9AMCHR1MEN1KMT2ANPC1 | |
| SCHEMBL23375700 | 0.73 | GRN (0.37) | RAB9AMCHR1MEN1KMT2ANPC1 | |
| SCHEMBL25801653 | 0.71 | OPRM1 (0.44) | — | |
| SCHEMBL25369762 | 0.69 | OPRM1 (0.36) | WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904350-A1 | N-(CYCLOPROPYLMETHYL)-5-(METHYLSULFONYL)-N-{1-[1-(PYRIMIDIN-2-YL)-1H-1,2,4-TRIAZOL-5-YL]ETHYL}BENZAMIDE DERIVATIVES AND THE CORRESPONDING PYRIDINE-CARBOXAMIDE DERIVATIVES AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-11-03 | — | — | EP | disclosed |