Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21462335 | 1.00 | RAPGEF3 (0.41) | RAPGEF3MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL936363 | 0.84 | CNR2 (0.41) | MEN1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL21486502 | 0.84 | OPRM1 (0.38) | MEN1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL31646837 | 0.83 | NOTUM (0.46) | MEN1ALDH1A1KMT2AMAPTNPC1 | |
| SCHEMBL22926217 | 0.82 | TPMT (0.50) | MEN1ALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29639686 | 0.82 | TPMT (0.50) | MEN1ALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL23976730 | 0.81 | PARP1 (0.39) | MEN1ALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL22497961 | 0.80 | NOTUM (0.52) | MEN1ALDH1A1KMT2AMAPTNPC1 | |
| SCHEMBL29659834 | 0.80 | NOTUM (0.52) | MEN1ALDH1A1KMT2AMAPTNPC1 | |
| SCHEMBL935382 | 0.80 | MEN1 (0.39) | MEN1ALDH1A1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003974-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2022-06-01 | — | — | EP | disclosed |