Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27387144 | 0.93 | HSP90AA1 (0.59) | HSP90AA1HDAC1AGTR1AGTR2HSP90AB1 | |
| SCHEMBL5291955 | 0.92 | AGTR1 (0.60) | HSP90AA1HDAC1AGTR1AGTR2HSP90AB1 | |
| SCHEMBL11013827 | 0.92 | AGTR1 (0.60) | HSP90AA1HDAC1AGTR1AGTR2HSP90AB1 | |
| SCHEMBL27389591 | 0.92 | HSP90AA1 (0.61) | HSP90AA1HDAC1AGTR1AGTR2HSP90AB1 | |
| Hydrochloric Acid SCHEMBL28122561 | 0.91 | AGTR1 (0.59) | HSP90AA1HDAC1AGTR1AGTR2HSP90AB1 | |
| SCHEMBL11014930 | 0.91 | AGTR1 (0.61) | HSP90AA1HDAC1AGTR1AGTR2HSP90AB1 | |
| SCHEMBL9214231 | 0.89 | AGTR1 (0.66) | HSP90AA1HDAC1AGTR1AGTR2HSP90AB1 | |
| SCHEMBL10615885 | 0.88 | HSP90AA1 (0.68) | HSP90AA1HDAC1AGTR1AGTR2HSP90AB1 | |
| SCHEMBL11449438 | 0.85 | HSP90AA1 (0.65) | HSP90AA1HDAC1AGTR1AGTR2HSP90AB1 | |
| SCHEMBL5292839 | 0.85 | HSP90AA1 (0.61) | HSP90AA1AGTR1AGTR2HSP90AB1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3272740-A2 | HIGH STABILITY DIIONIC LIQUID SALTS | Sigma-Aldrich Co. LLC (US) | 2018-01-24 | — | — | EP | disclosed |
| US-9782746-B2 | Polymeric ionic liquids, methods of making and methods of use thereof | THE UNIVERSITY OF TOLEDO (US) | 2017-10-10 | — | — | US | disclosed |
| US-20160114309-A1 | Polymeric Ionic Liquids, Methods of Making and Methods of Use Thereof | THE UNIVERSITY OF TOLEDO (US) | 2016-04-28 | — | — | US | disclosed |
| US-9249261-B2 | Polymeric ionic liquids, methods of making and methods of use thereof | THE UNIVERSITY OF TOLEDO (US) | 2016-02-02 | — | — | US | disclosed |
| US-8956445-B2 | High stability diionic liquid salts | SIGMA-ALDRICH CO. (US) | 2015-02-17 | — | — | US | disclosed |
| US-8734673-B2 | Boron selective ionic liquids and polymeric ionic liquids, methods of making and methods of use thereof | THE UNIVERSITY OF TOLEDO (US) | 2014-05-27 | — | — | US | disclosed |
| US-20140121387-A1 | High Stability Diionic Liquid Salts | SIGMA-ALDRICH CO. LLC (US) | 2014-05-01 | — | — | US | disclosed |
| EP-2682396-A1 | High stability diionic liquid salts | Sigma-Aldrich Co. (US) | 2014-01-08 | — | — | EP | disclosed |
| US-20120211696-A1 | HIGH STABILITY DIIONIC LIQUID SALTS | SIGMA-ALDRICH CO. LLC (US) | 2012-08-23 | — | — | US | disclosed |
| US-20120215005-A1 | High Stability Diionic Liquid Salts | SIGMA-ALDRICH CO. LLC (US) | 2012-08-23 | — | — | US | disclosed |
| US-8182581-B2 | use of these novel bis-cationic and/or bis-anionic ionic liquids as the stationary phase in a gas chromatographic column | SIGMA-ALDRICH CO. LLC (US) | 2012-05-22 | — | — | US | disclosed |
| US-20120111796-A1 | Boron Selective Ionic Liquids and Polymeric Ionic Liquids, Methods of Making and Methods of Use Thereof | UNIVERSITY OF TOLEDO (US) | 2012-05-10 | — | — | US | disclosed |
| US-8168830-B2 | use of these novel ionic liquids having bis-cation or bis-anion separated by bridging group as the stationary phase in a gas chromatographic column | SIGMA-ALDRICH CO. LLC (US) | 2012-05-01 | — | — | US | disclosed |
| US-20110236295-A1 | Polymeric Ionic Liquids, Methods of Making and Methods of Use Thereof | UNIVERSITY OF TOLEDO (US) | 2011-09-29 | — | — | US | disclosed |
| WO-2010017564-A1 | BORON SELECTIVE IONIC LIQUIDS AND POLYMERIC IONIC LIQUIDS, METHODS OF MAKING AND METHODS OF USE THEREOF | UNIVERSITY OF TOLEDO (US) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010017563-A1 | POLYMERIC IONIC LIQUIDS, METHODS OF MAKING AND METHODS OF USE THEREOF | UNIVERSITY OF TOLEDO (US) | 2010-02-11 | — | — | WO | disclosed |
| US-20080027231-A1 | High stability diionic liquid salts | SIGMA-ALDRICH CO. (US) | 2008-01-31 | — | — | US | disclosed |
| US-20060025598-A1 | High stability diionic liquid salts | ADVANCED SEPARATION TECHNOLOGIES INC. (US) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027231-A1 | High stability diionic liquid salts | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HDHD5, DAD1 | HSP90AA1 3240/4885HDAC1 2811/4885AGTR1 2264/4885 |
| US-20060025598-A1 | High stability diionic liquid salts | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, DCLK2, HDHD5 | HSP90AA1 3292/4885HDAC1 2994/4885AGTR1 2431/4885 |
| US-20120111796-A1 | Boron Selective Ionic Liquids and Polymeric Ionic Liquids, Methods of Making and Methods of Use Thereof | BCCIP, SLC6A12, BOLA2; BOLA2B | HSP90AA1 4401/4885HDAC1 4623/4885AGTR1 4206/4885 |
| US-20140121387-A1 | High Stability Diionic Liquid Salts | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, DCLK2, HDHD5 | HSP90AA1 3292/4885HDAC1 2994/4885AGTR1 2431/4885 |
| US-20120215005-A1 | High Stability Diionic Liquid Salts | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, DCLK2, HDHD5 | HSP90AA1 3292/4885HDAC1 2994/4885AGTR1 2431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.