Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | ADCY8 | P40145 | 3/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957525 | 0.86 | ADCY8 (0.40) | KIF11ADCY8ADCY1GPBAR1S1PR1 | |
| SCHEMBL31085070 | 0.82 | KIF11 (0.51) | KIF11ADCY8ADCY1GPBAR1TAS2R14 | |
| SCHEMBL313001 | 0.82 | KIF11 (0.51) | KIF11ADCY8ADCY1GPBAR1TAS2R14 | |
| SCHEMBL22728381 | 0.82 | ADCY8 (0.39) | KIF11ADCY8ADCY1GPBAR1S1PR1 | |
| SCHEMBL27803229 | 0.80 | HTT (0.48) | KIF11ADCY8ADCY1GPBAR1TAS2R14 | |
| SCHEMBL16959291 | 0.79 | ADCY8 (0.37) | KIF11ADCY8ADCY1GPBAR1S1PR1 | |
| SCHEMBL29528380 | 0.78 | TAS2R14 (0.50) | ADCY8ADCY1GPBAR1TAS2R14ALKBH5 | |
| SCHEMBL374174 | 0.78 | TAS2R14 (0.50) | ADCY8ADCY1GPBAR1TAS2R14ALKBH5 | |
| SCHEMBL16961054 | 0.78 | ADCY8 (0.38) | KIF11ADCY8ADCY1GPBAR1S1PR1 | |
| SCHEMBL2891169 | 0.77 | ADCY8 (0.43) | KIF11ADCY8ADCY1GPBAR1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903581-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS I | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |