Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978654 | 0.91 | ALDH1A1 (0.42) | HPGDSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL23978639 | 0.84 | KCNQ2 (0.42) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL30279401 | 0.82 | EPHX2 (0.46) | HPGDALDH1A1HTT | |
| SCHEMBL26495115 | 0.82 | EPHX2 (0.46) | HPGDALDH1A1HTT | |
| SCHEMBL24803360 | 0.82 | EPHX2 (0.46) | HPGDALDH1A1HTT | |
| SCHEMBL23978981 | 0.79 | POLB (0.48) | SMN1; SMN2KDM4EMEN1KMT2AHTT | |
| SCHEMBL23978691 | 0.77 | PRMT5 (0.36) | MEN1KMT2APOLB | |
| SCHEMBL23978642 | 0.77 | LNPEP (0.39) | KDM4EPOLB | |
| SCHEMBL23978682 | 0.74 | LNPEP (0.42) | ALDH1A1POLBGAA | |
| SCHEMBL23979049 | 0.74 | P2RX3 (0.36) | SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |