Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 2/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.37 |
| ▸ | ITGAV | P06756 | 3/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26103779 | 1.00 | CTSL (0.45) | CTSLKCNQ2KDM4EMAPTMAPK1 | |
| SCHEMBL23978812 | 1.00 | CTSL (0.45) | CTSLKCNQ2KDM4EMAPTMAPK1 | |
| SCHEMBL24805443 | 0.94 | CTSL (0.43) | CTSLKCNQ2KDM4EMAPTMAPK1 | |
| SCHEMBL23978987 | 0.84 | CTSL (0.40) | CTSLKCNQ2KDM4EANO1GLS | |
| SCHEMBL23978813 | 0.82 | KCNQ2 (0.44) | KCNQ2KDM4EMAPTITGB2ICAM1 | |
| SCHEMBL30279468 | 0.82 | KCNQ2 (0.44) | KCNQ2KDM4EMAPTITGB2ICAM1 | |
| SCHEMBL26107107 | 0.82 | KCNQ2 (0.44) | KCNQ2KDM4EMAPTITGB2ICAM1 | |
| SCHEMBL23978983 | 0.80 | LOXL2 (0.40) | ANO1ITGB1ITGAVITGA5ITGA4 | |
| SCHEMBL23978639 | 0.80 | KCNQ2 (0.42) | KCNQ2ANO1ITGB1ITGA5MEN1 | |
| SCHEMBL23978590 | 0.80 | KCNQ2 (0.39) | KCNQ2KDM4EMAPTITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916176-A | Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |
| EP-4142707-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | The Regents of the University of California (US) | 2023-03-08 | — | — | EP | disclosed |