Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 11/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 9/20 | 0.36 |
| ▸ | PARP1 | P09874 | 7/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10129830 | 0.77 | PARP10 (0.36) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL30279445 | 0.77 | PARP10 (0.36) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL10129821 | 0.74 | ACHE (0.50) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL30402278 | 0.74 | ACHE (0.50) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL30401909 | 0.71 | PARP1 (0.41) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL23978726 | 0.71 | PARP1 (0.41) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL23978853 | 0.69 | DHPS (0.44) | HTT | |
| SCHEMBL14842620 | 0.68 | ACHE (0.54) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL26505461 | 0.67 | MRGPRX4 (0.31) | PARP10PARP1F7F3MRGPRX4 | |
| SCHEMBL1759917 | 0.66 | NOTUM (0.56) | PARP10PARP11PARP1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |